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Videos uploaded by user “NEJMvideo”
NEJM Procedure: Deployment of an Endovascular Graft in an Abdominal Aortic Aneurysm
 
02:19
Aneurysm repair is a mechanical solution to the problem of progressive expansion of abdominal aortic aneurysm and the risk of rupture. Although open surgical repair, which has been the established approach, is very effective, it carries substantial risks from the extensive surgical procedure. Endovascular repair was developed to reduce the risks associated with open surgery and to provide a treatment option for patients who are not deemed to be surgical candidates.
Views: 113185 NEJMvideo
Cycling for Freezing Gait in Parkinson's Disease
 
01:50
A 58-year-old man with a 10-year history of idiopathic Parkinson's disease presented with an incapacitating freezing of gait. However, the patient's ability to ride a bicycle was remarkably preserved. (In Video 2, the patient is not wearing a safety helmet because in the Netherlands, wearing a safety helmet is neither required by law nor customary.) http://bit.ly/c4BQ2f
Views: 272779 NEJMvideo
Measurement of the Hepatic Venous Pressure Gradient (HVPG)
 
01:37
Measurement of the Hepatic Venous Pressure Gradient (HVPG)
Views: 37173 NEJMvideo
The Epidemiology of In-Flight Medical Emergencies
 
02:52
New research on medical emergencies aboard commercial airliners is summarized in this NEJM Quick Take, a short video animation. See the NEJM article, "Outcomes of Medical Emergencies on Commercial Airline Flights": http://www.nejm.org/doi/full/10.1056/NEJMoa1212052
Views: 28796 NEJMvideo
NEJM Procedure: Primary PCI for Myocardial Infarction with ST-Segmented Elevation
 
03:16
Reperfusion therapy (mechanical or pharmacologic) is indicated for patients with chest pain consistent with a myocardial infarction with a duration of 12 hours or less in association with ST-segment elevation greater than 0.1 mV in two or more contiguous electrocardiographic leads or a new (or presumed new) left bundle-branch block. Primary PCI is preferred if a skilled interventional cardiologist and catheterization laboratory with surgical backup are available and if the procedure can be performed within 90 minutes after initial medical contact with the patient.
Views: 36510 NEJMvideo
NEJM Procedure: Endoscopic Management of Acute Bleeding from a Peptic Ulcer
 
05:33
Acute upper gastrointestinal hemorrhage, which is defined as bleeding proximal to the ligament of Treitz, is a prevalent and clinically significant condition with important implications for health care costs worldwide. Negative outcomes include rebleeding and death, and many of the deaths are associated with decompensation of coexisting medical conditions precipitated by the acute bleeding event. This video focuses specifically on endoscopic management of acute bleeding from a peptic ulcer. See the August 28, 2008, Current Concepts review article: "Management of Acute Bleeding from a Peptic Ulcer" http://www.nejm.org/doi/full/10.1056/NEJMra0706113
Views: 74332 NEJMvideo
Two Videos Showing Fluoroscopy and Animation of the TAVI Procedure
 
02:23
Fluoroscopy with Videography Showing Deployment of the Valve: The valve is deployed during rapid right ventricular pacing. The crimped valve and support frame are expanded with underlying balloon inflation. Also seen are the transesophageal echocardiography probe and the temporary right ventricular pacing lead. Animation of the Complete Transfemoral Transcatheter Aortic-Valve Implantation (TAVI) Procedure: The procedure for transfemoral TAVI involves insertion of the sheath through the femoral artery, retrograde balloon aortic valvuloplasty, advancement of the TAVI system across the aortic valve, and subsequent deployment of the valve and support frame.
Views: 154854 NEJMvideo
Four Examples of Ataxia
 
02:42
Video 1—Friedreich's Ataxia: A patient with Friedreich's ataxia, a gait disorder due to both cerebellar and proprioceptive ataxia, has imbalance, staggers, and has difficulties in making a half-turn. Because of difficulties with tandem walking, the patient requires the intermittent support of a wall. The patient has dysmetria during nose--finger and finger chase tests, and instability in a standing position with the feet together because of cerebellar ataxia. There is an obvious loss of balance when the patient's eyes are closed because of the proprioceptive component of the ataxia. Saccadic ocular pursuit and square-wave jerks due to fixation instability are shown, as well as diffuse abolition of the reflexes and right extensor plantar reflex. Video 2—Ataxia with Oculomotor Apraxia Type 1: Choreic movement of the hands and trunk with cervical dystonia in a patient with ataxia with oculomotor apraxia type 1. Video 3—Ataxia Telangiectasia: Right horizontal gaze-evoked nystagmus and nasal as well as temporal telangiectasias in a patient with ataxia telangiectasia. Video 4—Oculomotor Apraxia Type 1: Oculocephalic dissociation in a patient with ataxia with oculomotor apraxia type 1. During the rotation of the head, a dissociation is expressed as a delay between the movement of the eyes following that of the head.
Views: 322304 NEJMvideo
Risk of Cancer in a CT-Discovered Nodule
 
02:34
New research on the malignancy risk of pulmonary nodules first identified on low-dose CT screening is summarized in a short animation, available at NEJM.org. See the NEJM article: Probability of Cancer in Pulmonary Nodules Detected on First Screening CT http://www.nejm.org/doi/full/10.1056/NEJMoa1214726
Views: 8526 NEJMvideo
The SPRINT Trial
 
01:49
Learn results from the SPRINT trial on intensive blood pressure management in less than 2 minutes with new NEJM Quick Take video summary. #AHA15 http://nej.md/1lfHkLD See the NEJM article, "A Randomized Trial of Intensive versus Standard-Blood Pressure Control":http://www.nejm.org/doi/full/10.1056/NEJMoa1511939
Views: 9946 NEJMvideo
PARADIGM-HF: A Concise Summary with Journal Club Questions
 
03:17
A three-minute summary of the PARADIGM-HF trial includes five Journal Club questions. See the NEJM article, "Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure": http://www.nejm.org/doi/full/10.1056/NEJMoa1409077 See the related editorial, "Neprilysin Inhibition — A Novel Therapy for Heart Failure": http://www.nejm.org/doi/full/10.1056/NEJMe1409898 See the related Perspective article: "Paradigm Shifts in Heart-Failure Therapy — A Timeline": http://www.nejm.org/doi/full/10.1056/NEJMp1410241
Views: 6479 NEJMvideo
Ischemic Optic Neuropathies
 
05:14
A new review article covers the diagnosis, pathophysiological features, and prognosis of ischemic optic neuropathy, a relatively common cause of visual loss in older patients, including visual loss after cardiac surgery. It must be distinguished from inflammatory optic neuritis. Read the full article: http://www.nejm.org/doi/full/10.1056/NEJMra1413352
Views: 20653 NEJMvideo
Intravenous Fluids and Patient Outcomes
 
02:13
Intravenous administration of isotonic crystalloid fluids is one of the most common medical therapies, but whether the composition of the fluid has an effect on outcomes has not been known. New research findings are summarized in this short video. Full SALT-ED trial results: http://nej.md/2F6uHQF Watch more Quick Take videos: http://nej.md/quick-take
Views: 7763 NEJMvideo
Leadless Cardiac Pacemaker.
 
01:21
The video shows the technique for implantation of the Nanostim leadless cardiac pacemaker. See the NEJM article, "Percutaneous Implantation of an Entirely Intracardiac Leadless Pacemaker": http://www.nejm.org/doi/full/10.1056/NEJMoa1507192
Views: 15488 NEJMvideo
A Novel Hemophilia A Therapy
 
01:56
Severe hemophilia A is often treated with infusions of factor VIII. But the infusions are burdensome, and antibodies develop in about 30% of patients. Would emicizumab, which mimics the function of factor VIII, reduce these problems? New research findings are summarized in a new NEJM Quick Take video. Learn more at http://nej.md/1WoeHdF
Views: 6299 NEJMvideo
Maneuvers to Diagnosis and Treat Benign Paroxysmal Positional Vertigo
 
08:52
Videos show the patterns of nystagmus that are diagnostic of the two most common types of BPPV and demonstrate the movements of the body that should be performed to treat each type. See the NEJM Clinical Practice article, "Benign Paroxysmal Positional Vertigo": http://www.nejm.org/doi/full/10.1056/NEJMcp1309481
Views: 423847 NEJMvideo
Filtered Sunlight for Newborns.
 
01:53
Neonatal jaundice is a common threat to newborns worldwide. Expensive phototherapy equipment is impractical in developing countries. Is sunlight an effective alternative? New research findings are summarized in a two-minute NEJM Quick Take video. See the NEJM article, "A Randomized Trial of Phototherapy with Filtered Sunlight in African Neonates": http://www.nejm.org/doi/full/10.1056/NEJMoa1501074
Views: 18479 NEJMvideo
The Risk of Stroke after Transient Ischemic Attack
 
02:12
The elevated risk of stroke or acute coronary syndrome after a transient ischemic attack can be estimated with a scoring system in which a high score indicates the need for urgent evaluation. Has this approach led to a reduction in risk? New research findings are summarized in this NEJM Quick Take video. Learn more at http://nej.md/1VgADsh
Views: 8281 NEJMvideo
Mass Intoxication with a Synthetic Cannabinoid
 
02:19
In July 2016, emergency services in Brooklyn responded to a scene of mass intoxication of 33 persons who had been exposed to an “herbal incense” product. How was the cause of their zombielike behavior identified? New research findings are summarized in this short video. Full study: http://nej.md/2gxxh1J
Views: 7545 NEJMvideo
Nut Consumption and Mortality
 
02:56
The NEJM Original Article, "Association of Nut Consumption with Total and Cause-Specific Mortality," is summarized in an NEJM Quick Take. See the study: http://www.nejm.org/doi/full/10.1056/NEJMoa1307352
Views: 20633 NEJMvideo
Reducing the Risk of Preeclampsia in Pregnant Women
 
01:54
Preterm preeclampsia is an important cause of maternal and perinatal death and complications. Low-dose aspirin has been recommended for pregnant women considered to be at high risk. New research findings are summarized in this short video. Full study results: http://nej.md/2todAEI Watch more Quick Take videos: http://nej.md/quick-take
Views: 11892 NEJMvideo
NEJM Procedure: Thrombus Aspiration
 
01:39
In an occluded infarct-related artery, reperfusion can be achieved by the standard means of primary percutaneous coronary intervention or by the new method of thrombus aspiration, followed by stenting, as depicted in this video.
Views: 23051 NEJMvideo
Quick Take: Cardiovascular Safety of Celecoxib
 
02:47
NSAIDS such as ibuprofen and naproxen can provide pain relief but may increase the risk of GI bleeding. Previous studies showed that high doses of celecoxib increased cardiovascular harm, but the safety of modest doses was unclear. New research findings are summarized in this short video. Access the full Original Article: http://nej.md/2fynoCi
Views: 8461 NEJMvideo
Treating Latent Tuberculosis
 
01:43
Isoniazid is the recommended treatment for latent tuberculosis infection, but its benefit is substantially reduced because of hepatotoxicity and poor rates of regimen completion. New research findings are summarized in this short video. Full study: https://nej.md/2OycQ6Z Watch more Quick Take videos: http://nej.md/quick-take
Views: 3296 NEJMvideo
The BRIDGE Trial
 
01:36
Patients with atrial fibrillation are at increased risk of stroke. Warfarin anticoagulation is often used to reduce risk, but it is usually stopped perioperatively. Temporary “bridging” with heparin is common, but is it necessary? New research findings are summarized in a short video. See the NEJM article: "Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation": http://www.nejm.org/doi/full/10.1056/NEJMoa1501035
Views: 3802 NEJMvideo
Catheter-Associated UTI Prevention
 
02:01
Indwelling urinary catheters are commonly used in hospitals and can lead to preventable catheter-associated UTI. How can rates of catheter-associated UTI be reduced in hospitals? New research findings are summarized in a new NEJM Quick Take. Learn more at http://nej.md/1WoeHdF
Views: 8255 NEJMvideo
Influenza and Acute Cardiovascular Events
 
02:18
Several studies have advanced the hypothesis that influenza may trigger acute cardiovascular events, but most were underpowered or limited by inaccurate diagnostic methods or had designs that were susceptible to bias. New research findings are summarized in this short video. Full study results: http://nej.md/2DCGCG4
Views: 3093 NEJMvideo
Treating Neonatal Abstinence Syndrome
 
01:44
Babies who were exposed to opioids in utero are at risk for neonatal abstinence syndrome. New research findings are summarized in this short video. Full study: http://nej.md/2p8NrUn View more Quick Take videos: http://nej.md/quick-take
Views: 6031 NEJMvideo
MR CLEAN — A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke
 
02:25
A new Quick Take video summary gives an overview of the recently published results of the MR CLEAN trial, which found that for patients with acute ischemic stroke caused by a proximal occlusion of the anterior circulation, intra-arterial therapy administered within six hours of symptom onset can improve functional outcomes. Read the full NEJM Original Article: http://www.nejm.org/doi/full/10.1056/NEJMoa1411587
Views: 13509 NEJMvideo
Reducing Exacerbations in COPD
 
02:04
Studies have shown that triple inhaled therapy has benefits in patients at risk for frequent or severe COPD exacerbations, but the therapy has required the use of multiple inhalers several times a day. Full study: https://nej.md/2I6BfjW Watch more Quick Take videos: http://nej.md/quick-take
Views: 2962 NEJMvideo
Parasite-Derived Cancer
 
02:14
Can malignant transformation of parasite cells cause neoplasms in an immunosuppressed host? New research findings are summarized in this new Quick Take video. See the NEJM article, "Malignant Transformation of Hymenolepis nana in a Human Host": http://www.nejm.org/doi/full/10.1056/NEJMoa1505892
Views: 33079 NEJMvideo
Benefits and Risks of Salt Consumption
 
02:56
What do we know about salt and cardiovascular disease? Current guidelines and statistics are summarized in a short animation.
Views: 11133 NEJMvideo
Preventive Therapy for Chronic Migraine
 
02:12
Patients with chronic migraine have functional impairment and reduced quality of life. Preventive treatment is recommended but may be underused or ineffective. New research findings are summarized in this short video. Full study: http://nej.md/2zzU0Ve Watch more Quick Take videos: http://nej.md/quick-take
Views: 3124 NEJMvideo
The ANNEXA-A and ANNEXA-R Trials
 
01:41
Factor Xa inhibitors, used to prevent and treat thromboembolism, can cause bleeding. Andexanet was designed to reverse the anticoagulant effects of these inhibitors. Is andexanet efficacious? New research findings are summarized in this short video. See the NEJM article, "Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity (ANNEXA)": http://www.nejm.org/doi/full/10.1056/NEJMoa1510991
Views: 3813 NEJMvideo
Body Positioning after Acute Stroke
 
01:47
Small, nonrandomized studies have shown that body positioning after an acute stroke may affect outcomes. New research findings are summarized in this short video. Full study: http://nej.md/2sAPwuU Watch more Quick Take videos: http://nej.md/quick-take
Views: 3740 NEJMvideo
Frontiers in Medicine: A Look at CAR T-Cell Therapy
 
01:32
In this video, the concepts, process, and uses of CAR T-cell therapy are explained. Read the full review on chimeric antigen receptor therapy, the first article in the Frontiers in Medicine series: https://nej.md/2tPkmBW
Views: 2092 NEJMvideo
NEJM Procedure: Radiofrequency Ablation in Barretts Esophagus with Dysplasia
 
06:44
Barrett's esophagus, a condition of intestinal metaplasia of the esophagus, is associated with an increased risk of esophageal adenocarcinoma. In patients with dysplastic Barrett's esophagus, radiofrequency ablation was associated with a high rate of complete eradication of both dysplasia and intestinal metaplasia and a reduced risk of disease progression.
Views: 22816 NEJMvideo
Outcomes with Oxygen in Suspected Myocardial Infarction
 
01:41
Supplemental oxygen has been routinely recommended for patients with suspected acute MI, but too much oxygen may contribute to reperfusion injury. Is routine use of oxygen warranted? New research findings are summarized in this short video.
Views: 2790 NEJMvideo
Radium-223 and Metastatic Prostate Cancer
 
02:14
In a study involving men with castration-resistant prostate cancer and bone metastases, the alpha emitter radium-223 significantly prolonged survival, as compared with placebo, and was associated with fewer adverse events. See the NEJM article: http://www.nejm.org/doi/full/10.1056/NEJMoa1213755
Views: 10635 NEJMvideo
Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents
 
02:07
Effective antivirals are needed for the treatment and prevention of influenza virus infections but circulating influenza viruses are increasingly resistant to the antiviral agents currently in use. Full study: https://nej.md/2Q4l6wt Browse the Quick Take video archive: http://nej.md/quick-take
Views: 3097 NEJMvideo
Preventing Thrombosis after PCI
 
02:31
Triple therapy (oral anticoagulation plus two antiplatelet agents) is the standard of care after PCI in patients with atrial fibrillation, but it is associated with a high risk of major bleeding. New research findings are summarized in this short video. Full study: http://nej.md/2wB85nM Watch more Quick Take videos: http://nej.md/quick-take
Views: 3184 NEJMvideo
Treatment for Postinfectious Hydrocephalus in Infants
 
02:09
In sub-Saharan Africa, a large number of infants are affected by hydrocephalus that develops after neonatal ventriculitis and is often associated with poor developmental outcomes. Full study: http://nej.md/2BG0k1H Watch more Quick Take videos: http://nej.md/quick-take
Views: 3415 NEJMvideo
Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation
 
01:59
Catheter ablation is an invasive procedure; patients usually receive periprocedural anticoagulants for several weeks. New research findings are summarized in this short video. Full study: http://nej.md/2nsLuSz Watch more Quick Take videos: http://nej.md/quick-take
Views: 3135 NEJMvideo
Otoscopic Signs of Acute Otitis Media
 
01:14
1. Air-fluid level 2. Full, bulging tympanic membrane 3. Bulla formation;  Otoscopic Signs at the End of Treatment: Complete Resolution 4. Complete resolution of otoscopic signs of acute otitis media; middle-ear fluid; Otoscopic Signs at the End of Treatment: Improvement 5. Partial resolution of otoscopic signs of acute otitis media; middle-ear fluid with air--fluid level remains 6. No improvement in otoscopic signs of acute otitis media; Otoscopic Signs at the End of Treatment: Failure 7. No improvement in otoscopic signs of acute otitis media  8. Perforation of tympanic membrane.
Views: 137044 NEJMvideo
Preventing Vascular Events in Diabetes
 
01:37
The benefit of aspirin for patients with cardiovascular disease is well established, but whether there is a preventive benefit — especially in patients with #diabetes, who are at substantial risk — has not been clear. Full study: https://nej.md/2DGJJNM Browse the Quick Take archive: http://nej.md/quick-take
Views: 1689 NEJMvideo
Shorter Antibiotic Treatment for Otitis Media
 
02:14
Acute otitis media is the most common indication for which U.S. children receive antibiotics, usually for 10 days. Given growing concern about antimicrobial resistance, can treatment duration be shortened without changing outcomes? New research findings are summarized in a short video. Read the full study: nej.md/2hSUhgj
Views: 4541 NEJMvideo
Liraglutide and Cardiovascular Outcomes
 
01:51
Liraglutide lowers blood glucose and is associated with weight loss, lowered BP, and an increase in heart rate. Would treatment with liraglutide have a beneficial effect on cardiovascular outcomes in patients with diabetes? New research findings are summarized in a short video. Learn more at http://nej.md/1WoeHdF
Views: 5420 NEJMvideo
Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease
 
02:09
Patients with sickle cell disease may experience pain crises related to P-selectin, which contributes to vaso-occlusion. Would an antibody that blocks binding to P-selectin reduce the frequency of pain crises? New research findings are summarized in this short video. Full study: http://www.nejm.org/doi/full/10.1056/NEJMoa1611770
Views: 3930 NEJMvideo
Cardiovascular Outcomes in Patients with Diabetes
 
02:10
Studies have shown the importance of intensive glucose lowering, blood-pressure control, and use of statins to reduce cardiovascular risk and mortality in patients with diabetes, but long-term trends in such patients are unknown. Full study: http://nej.md/2o6mCzN Watch more Quick Take videos: http://nej.md/quick-take
Views: 2224 NEJMvideo
Increase of Telomere Length by a Sex Hormone
 
01:47
Telomeres shorten with DNA replication, and shorter telomeres are linked to disease. Androgenic hormones regulate expression of the telomerase gene. Would treatment with synthetic androgen slow the shortening of telomeres? New research findings are summarized in this NEJM Quick Take video. Learn more at http://nej.md/1WoeHdF
Views: 2428 NEJMvideo

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